Migration of S1P2-deficient GC Bcells

Two-photon imaging of the germinal center (GC) in the lymph node demonstrated that S1P2-deficient GC B cells (green) were migrating around the perimeter of the GC with higher motility compared to wild-type GC B cells (cyan). Naive B cells (red) were visulalized to reveal the shape of the GC. Nat. Immunol. 12: 672-680; 2011.